Veranstaltungshinweis: MTB Seminar Talk, 25. Mai

Data Infrastructures for Molecular Tumor Boards

Date: Thursday 25.05.2023, 10.30: The seminar will take place in presence in our seminar room and will be online (Link: streamed. 

Speaker: Prof. Dr. Oliver Kohlbacher (Dept. of Computer Science, University of Tübingen, Center for Bioinformatics and Medical Informatics, University of Tübingen, Institute for Translational Bioinformatics, University Hospital Tübingen

Topic: Data Infrastructures for Molecular Tumor Boards

Abstract: Molecular Tumor Boards (MTBs) are an essential component in the implementation of personalized oncology. They are interdisciplinary boards analyzing and integrating complex multimodal data (omics data, clinical data, imaging data, etc.) in order to provide an optimal personalized care plan for patients who typically have no or few other treatment options available. The multimodality of the data,  the complex clinical processes, and the interdisciplinary nature of the MTB process pose significant challenges in the implementation of MTBs. 

Supporting these processes can be enabled by data infrastructures mobilizing, standardizing, and integrating the required data. We will discuss several tools developed in our lab in recent years, including PeCaX, the Personalized Cancer Explorer and related tools for annotating and visualizing omics data for MTBs. We then 
present bwHealthCloud, a federated infrastructure developed within the Centers for Personalized Medicine in Baden-Württemberg, which enables the analysis of MTB cases across four different university hospitals. The implementation of bwHealthCloud is currently being extended to a nationwide MTB data infrastructure, DNPM:dip as partof the German Network for Personalized Medicine and we will discuss the technical and organizational challenges associated with this expansion.

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